OUR CAPABILITIES
Products and services
Gene editing
We have extensive experience in producing gene edited pluripotent cell products. Whether your end outcome is a reporter line for research purposes, mutation corrected models for drug screening or functional assessment of gene knock-in/out, we can work with you to design a suitable tool to meet your research goals.
We offer multiple options for generation of reporter lines to investigate your marker of interest in hESC or IPSC. For proof of principle studies we recommend using our custom "Chassis" MEL2 embryonic backbone, specifically designed to permit quick insertion of your marker of interest into the AAVS1 safe harbour locus.
Reporter lines
We have substantial experience with the use of numerous modifications of Cas9 protein which have been recruited to perform the tasks of either activation and repression of the desired gene targets.
Mutation correction
We have extensive experience (>10 years) of assisting clients in translating their science and novel therapeutic targets to support clinical end points, by ensuring we always focus on quality in developing the cell line.
Knock in/knock out models
We have extensive experience (>10 years) of assisting clients in translating their science and novel therapeutic targets to support clinical end points, by ensuring we always focus on quality in developing the cell line.