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Somatic Cell Reprogramming to hiPSC

We offer reprogramming of adult somatic cells to induced pluripotent stem cell lines using the latest traceless methods. StemCore staff have a proven track record of successful reprogramming to create high quality, well characterised iPSCs from a range of human cell types both wild-type and with a disease phenotype.

Reprogramming workflow.png

  • Generation of iPSC from adult somatic cells

  • Reprogramming using Sendai, mRNA, or client-preferred method

  • Reprogramming process adaptation based-on experience in managing > hundreds of cell reprogramming projects.​​

Extensive characterisation for establishing high-quality iPSC lines including:​

  • Markers of the undifferentiated and differentiated state

  • Genomic integrity 

  • Additional characterisation according to clients' preferences

  • Selection of pre-iPSC colony by highly-experienced research specialist 

  • Manual or automated pre-iPSC colony picking

  • Colony expansion ​and banking with the highest quality and purity i.e., absence of partially reprogrammed cells

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